Efficacy and safety of posaconazole for chronic pulmonary aspergillosis: next strategy against the threat of azole-resistant Aspergillus infection
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چکیده
Right © 2010 by the Infectious Diseases Society of America; This is a pre-copyediting, author-produced PDF of an article accepted for publication in Clinical infectious diseases following peer review. The definitive publisher-authenticated version Clinical infectious diseases, 51(12), pp.1392-1394; 2010 is available online at: http://cid.oxfordjournals.org/content/51/12/1392.full. NAOSITE: Nagasaki University's Academic Output SITE
منابع مشابه
Posaconazole prophylaxis in experimental azole-resistant invasive pulmonary aspergillosis.
We investigated the efficacy of posaconazole prophylaxis in preventing invasive aspergillosis due to azole-resistant Aspergillus fumigatus isolates. Using a neutropenic murine model of pulmonary infection, posaconazole prophylaxis was evaluated using three isogenic clinical isolates, with posaconazole MICs of 0.063 mg/liter (wild type), 0.5 mg/liter (F219I mutation), and 16 mg/liter. A fourth i...
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